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Cellular senescenceSenescent cells, the SASP, and the drugs that clear or quiet them.
Aging clocksEpigenetic, blood-based and other measures of biological age.
mTOR & rapamycinNutrient sensing through mTOR, and the rapalogs that dial it down.
Partial reprogrammingYamanaka factors, epigenetic reprogramming and cellular rejuvenation.
NAD+ & sirtuinsNAD+ precursors, sirtuins and the metabolism of aging cells.
MitochondriaMitochondrial function, mitophagy and energy decline with age.
Dietary restrictionCaloric restriction, fasting and time-restricted eating.
GLP-1 drugsSemaglutide, tirzepatide and what incretin drugs do to aging.
InflammagingChronic low-grade inflammation and the aging immune system.
Brain agingCognitive aging, neurodegeneration and the aging brain.

ELN

GeneHomo sapiens1 paperHGNC 3327NCBI Gene 2006Taxon 9606

Cells1

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Enhanced Extracellular Matrix Synthesis-Related Responses Induced by Ubiquinol-10 Derivatives in Human Dermal Fibroblasts

CellsBioFactors

·Yesterday

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CDKN1A1
COL1A11
CXCL81
Cellular senescence1
IL61
MMP11
MMP31
Mitochondrial biogenesis (PGC-1α)1
Mitochondrial dysfunction1
Oxidative stress and ROS signalling1
Senescence-associated secretory phenotype (SASP)1
Adenosine triphosphate1
Ascorbic acid1
Coenzyme Q101
Hyaluronic acid1
Skin aging1

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