Mitochondrial-Targeted Phytochemicals in Reproductive Aging: Mechanisms and Translational Potential
Reproductive medicine and biology · Halim B et al. · Paper published 1 Jan 2026
We haven’t written this paper up. Its abstract belongs to the publisher, so read it at the source.
The paper
Mitochondrial-Targeted Phytochemicals in Reproductive Aging: Mechanisms and Translational Potential
Halim B, Lubis HP, Syahputra RA
Reproductive medicine and biology · 1 Jan 2026 · Peer-reviewed
- Relevance
- Core geroscience
- News value
- Routine
- Evidence
- Review
- Status
- Peer-reviewed
More on Mitochondria
See allCardiolipin loss drives muscle fiber shifts during aging via a nuclear receptor
Restoring cardiolipin synthesis in knockout mice reversed muscle atrophy and prevented premature death.
Nature aging · Finger F et al.
Early-life mitochondrial DNA mutations drive age-related pathology in mice
Manipulating mitochondrial fusion can alter tissue-specific selection against deleterious variants that arise early in development.
bioRxiv · Shemtov SJ et al.
Inhibiting miR-128-3p restores muscle mass and function in aged mice
The microRNA inhibitor also improved cardiac outcomes after infarction and reduced pathology in mouse and pig models of muscular dystrophy.
bioRxiv : the preprint server for biology · Boldridge MA et al.
Prodh2 inhibition alleviates muscle atrophy and restores strength in COPD mice
TNF-alpha triggers a mitochondrial immune pathway via Prodh2 that damages myoblasts, while silencing the enzyme restores muscle strength in mice.
Aging cell · Chen G et al.
Depp1 drives muscle loss under fasting and low oxygen in mice
The study reveals that the protein localizes to mitochondria to regulate autophagy and mitochondrial degradation during nutrient and oxygen limitation.
bioRxiv · Qayyum S et al.