POU3F2

Gene1 paper2 findingsHGNC 9215NCBI Gene 5454Taxon 9606

  • Animals1

Effects

2

Stem cell differentiation

downin mice1

1 study
  1. POU3F2 decreases stem cell differentiation in mice.

    Animalsmelanocyte-specific deletionhair bulb

    BRN2 protects against radiation-induced hair greying in mice · bioRxiv · 4 Oct 2026 · Preprint

Stem cell differentiation →

Hair depigmentation

downin mice1

1 study
  1. POU3F2 protects against hair depigmentation in mice.

    Animalsfollowing ionizing radiationhair follicle

    BRN2 protects against radiation-induced hair greying in mice · bioRxiv · 4 Oct 2026 · Preprint

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bioRxivAnimalsPreprint

BRN2 protects against radiation-induced hair greying in mice

In mice exposed to ionizing radiation, deleting Brn2 altered DNA damage responses and triggered permanent hair depigmentation linked to melanocyte…In mice exposed to ionizing radiation, deleting Brn2 altered DNA damage responses and triggered permanent hair depigmentation linked to melanocyte stem cell depletion.