CHEK2
Gene1 paper1 findingHGNC 16627MGI 1355321NCBI Gene 11200Taxon 9606
- Animals1
Upstream
1Ovarian aging
upin mice1
1 study
Ovarian aging
upin mice1
Ovarian aging increases CHEK2 in mice.
Animalsaged mice and human ovarian somatic cells
Inhibiting CHK2 improves oocyte quality and reduces ovarian inflammation in aged mice · bioRxiv · 1 Oct 2026 · Preprint
Latest
1bioRxivAnimalsPreprint
Inhibiting CHK2 improves oocyte quality and reduces ovarian inflammation in aged mice
A multi-omic analysis shows that defective luteal resolution and CHK2-driven inflammation drive ovarian aging, but drug inhibition restores oocyte…A multi-omic analysis shows that defective luteal resolution and CHK2-driven inflammation drive ovarian aging, but drug inhibition restores oocyte maturation.