ADRB2

Gene2 papers4 findingsHGNC 286NCBI Gene 154Taxon 9606

A preprint review links ADRB2 to higher myocardial infarction risk in humans with the rs1042714 GG genotype, lifespan in men, and body fat differences between rs1042714 Gln/Gln carriers and Gln/Glu or Glu/Glu carriers.

  • Humans1

Associations

4

Body fat

downin humans1

1 study
  1. ADRB2 is associated with body fat in humans (p = 0.050 and p = 0.009).

    Reviewcarriers of the Gln/Gln genotype vs Gln/Glu and Glu/Glu (rs1042714)

    Influence of the ADRB2 Gene on Sporting Ability and the Human Body: A Literature Review · Preprints.org · 24 Sep 2026 · Preprint

Myocardial infarction

upin humans1

1 study
  1. ADRB2 raises the risk of myocardial infarction in humans (3.3-fold (p = 0.021)).

    ReviewGG genotype of rs1042714

    Influence of the ADRB2 Gene on Sporting Ability and the Human Body: A Literature Review · Preprints.org · 24 Sep 2026 · Preprint

Myocardial infarction →

Lifespan

upin humans1OR 1.49

1 study
  1. ADRB2 is associated with lifespan in humans (OR = 1.49, p = 0.0007).

    Reviewin menmales

    Influence of the ADRB2 Gene on Sporting Ability and the Human Body: A Literature Review · Preprints.org · 24 Sep 2026 · Preprint

Mortality

upin humans1HR 2

1 study
  1. ADRB2 is associated with mortality in humans (HR, 2.00 [95% CI, 1.65-2.43]).

    “ADRB2 p.Arg175Arg (rs1042718) CC genotype was associated with mortality risk among ASCVD participants with CHIP clones (HR, 2.00 [95% CI, 1.65-2.43], P<0.0001)”

    Humansp.Arg175Arg (rs1042718) CC genotype among ASCVD participants with CHIP clones18-year median follow-up

    Genetic βAR Signaling Modifies Clonal Hematopoiesis-Associated Mortality in Patients with Atherosclerotic Cardiovascular Disease · Research Square · 22 Aug 2026 · Preprint

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