Polycystic kidney disease
- Animals5
Associations
1Mortality
upin mice1
1 study
Mortality
upin mice1
Polycystic kidney disease raises the risk of mortality in mice.
“Thus, our results indicated that PKD is the main reason of early mortality in bcl-2 deficient mice.”
Animalsbcl-2 deficient mice with kidney-sparing hBCL-2 rescue
Renal failure causes early death of bcl-2 deficient mice
Mechanisms of ageing and development18 Apr 2006
Trial sponsors
1 trialPhase 2/371 people
Seoul National University Hospital
1 trialPhase 2/344 people
University of Kansas Medical Center
1 trialPhase 236 people
1 trialPhase 218 people
1 trialPhase 210 people
1 trialPhase 1/230 people
Latest
7 in 12 monthsChinese Journal of Geriatrics
Research progress on targeting cellular senescence for the treatment of autosomal dominant polycystic kidney disease
ReviewCellular senescence
The Lancet Neurology
Prevalence of unruptured intracranial aneurysms according to comorbidities, risk factors, country, and time period: a systematic review and meta-analysis
Meta-analysis of observational studiesPopulations
Science Progress
Association of semaglutide use with kidney outcomes in adults with ADPKD: A propensity score-matched real-world study
Cohort study of 45,613 peopleSemaglutide
Metabolism Open
Ketogenic dietary interventions for autosomal-dominant polycystic kidney disease (ADPKD): a systematic review and synthesis without meta-analysis (SWiM) of observational and interventional studies
Systematic review of studies in peopleKidney
Journal of the American Society of Nephrology
α -Klotho Promotes Cell Death and Suppresses Inflammation through TNF-Cellular Inhibitor of Apoptosis Protein 1 Signaling in Autosomal Dominant Polycystic Kidney Disease
Experiments in miceKidney
Clinical Journal of the American Society of Nephrology
The Need for Novel Therapeutic Directions in Autosomal Dominant Polycystic Kidney Disease Patient Care
ReviewKidney
Current Opinion in Nephrology and Hypertension
Therapies in autosomal dominant polycystic kidney disease: beyond tolvaptan
ReviewKidney
Kidney International
Cellular senescence and its association with aldose reductase promote cyst growth in autosomal dominant polycystic kidney disease
Experiments in miceKidney