Osteoporotic fractures

Disease7 papers2 findingsMeSH D058866

  • Humans6

Associations

2

Multidomain lifestyle intervention

downin humans1HR 0.746

1 study
  1. Multidomain lifestyle intervention lowers the risk of osteoporotic fractures in humans (HR 0.746, 95% CI 0.564–0.987).

    Humansnormal BMDfemales

    Cumulative Lifestyle Score and Osteoporotic Fracture Risk by Bone Mineral Density Category in a Nationwide Korean Cohort of 66- Year-Old Women · Research Square · 30 Sep 2026 · Preprint

Multidomain lifestyle intervention →

History of falls

upin humans1

1 study
  1. History of falls are associated with osteoporotic fractures in humans.

    “Fallers had poorer physical and psychosocial health, greater gait variability, and a higher risk of osteoporotic fractures.”

    Humansin older adults with a history of falls

    Rationale, Design, and Baseline Characteristics of the TARGET (Targeted Assessment and Recruitment of Geriatrics for Effective Fall Prevention Treatments) Cohort of Older Adults for Assessing Fall and Fracture Risk: Prospective Cohort Study · JMIR aging · 25 Sep 2026

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Calcified Tissue InternationalHumans

Physical performance predicts fracture risk in older adults

In older men, a five-variable physical model beat FRAX without bone scans, raising 10-year fracture discrimination by an area under the curve of…In older men, a five-variable physical model beat FRAX without bone scans, raising 10-year fracture discrimination by an area under the curve of 0.052.

Diabetes, Obesity & MetabolismHumans

Genetically proxied GIP pathway links to lower fracture risk

Scaled to lower BMI, genetically proxied GIP-GIPR perturbation tracked with lower odds of major osteoporotic fractures (OR 0.80) and spine-and-hip…Scaled to lower BMI, genetically proxied GIP-GIPR perturbation tracked with lower odds of major osteoporotic fractures (OR 0.80) and spine-and-hip fractures (OR 0.68).