Neurodegenerative diseases
Disease6 papersMeSH D019636
Latest
30CellsPreprint
Rank normalization resolves distinct proteome degradation pathways in cultured cells
A percentile-based normalization method reveals substrate preferences between proteasomal and lysosomal clearance systems in cultured cells.
bioRxiv · Gao Z et al.
Human neurons accumulate far more mutations over lifespan than shorter-lived mammals
Cortical neurons gain mutations at similar yearly rates across six species, leaving aged humans with uniquely high mutational burdens and transcriptomic dysregulation.
bioRxiv : the preprint server for biology · Caglayan E et al.
The microbiota-proteostasis axis: implications in neurodegenerative diseases
ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
Cellular and systemic modifiers of alpha-synuclein proteostasis
ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
Proteostasis (in)action: the role of co-pathologies in neurodegenerative disease
ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
Differential proteostasis imbalance and the molecular basis of distinct synucleinopathies and tauopathies
ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
From aggregate structure to disease trajectory: the role of the proteostasis network
ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
Neuroinflammation and Autophagy in Neurodegeneration: Cellular Mechanisms and Therapeutic Strategies
ReviewCNS & neurological disorders drug targets
Redox-Mitochondrial Crosstalk in Neurotoxicity: Regulated Cell Death Pathways and Neuroprotective Strategies
ReviewAgeing research reviews