Liver pathology

There are 6 papers on liver pathology in aging research: 1 observational study in people, 3 in animals, 2 reviews. The newest story, Oct 19, 2026: “Mice lacking an inflammation protein had a longer median lifespan”.

Disease

6 papers study it48 more mention it3 findings

1 new paper in 30 daysSee all 54 papers on liver pathology

“Subjects with severe LP displayed a higher frequency of Alzheimer's type II astrocytes compared to those with no, or mild, LP.”
Alcohol consumers with liver pathology rarely display α-synuclein pathologyActa neuropathologica2024doi:10.1007/s00401-024-02772-4
  • Humans1
  • Animals3

Associations

3

Dementia

downin humans1

1 study
  1. Liver pathology is associated with dementia in humans (severe versus mild liver pathology) (13% with severe LP versus 30% with mild LP).

    “dementia was observed in 30% of those with mild LP when compared with 13% of those with severe LP.”

    Humanssevere versus mild liver pathology

    Alcohol consumers with liver pathology rarely display α-synuclein pathology

    Acta neuropathologica

More on Dementia

Alzheimer's type II astrocytes

upin humans1

1 study
  1. Liver pathology is associated with Alzheimer's type II astrocytes in humans (severe versus no or mild liver pathology).

    “Subjects with severe LP displayed a higher frequency of Alzheimer's type II astrocytes compared to those with no, or mild, LP.”

    Humanssevere versus no or mild liver pathologybrain

    Alcohol consumers with liver pathology rarely display α-synuclein pathology

    Acta neuropathologica

More on Alzheimer's type II astrocytes

Hypomagnesemia

upin reviews1

1 study
  1. Hypomagnesemia raises the risk of liver pathology with aging.

    “Additionally, risk of developing liver pathologies increases with age, and hypomagnesemia may be a contributing factor.”

    Reviewwith agingliver

    Magnesium and Liver Metabolism Through the Lifespan

    Advances in nutrition (Bethesda, Md.)

More on Hypomagnesemia

Latest

Dec 2025: 0Jan 2026: 2Feb 2026: 2Mar 2026: 0Apr 2026: 0May 2026: 1Jun 2026: 0Jul 2026: 0Aug 2026: 1Sep 2026: 0Oct 2026: 1Nov 2026: 07 papers in 12 months
bioRxiv

Mice lacking an inflammation protein had a longer median lifespan

An animal experiment found longer survival and marked resistance to age-related liver decline in mice genetically lacking the protein.An animal experiment found longer survival and marked resistance to age-related liver decline in mice genetically lacking the protein.

Preprint: mouse studyMechanisms

See all 54 papers on liver pathology