Lipotoxicity

Disease

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Signal Transduction and Targeted Therapy

Inotodiol preserves muscle mass and function in aged mice

The mycosterol restores mitochondrial metabolism by activating the LXRbeta-SIRT3-PGC-1alpha pathway to counter age-related muscle decline.The mycosterol restores mitochondrial metabolism by activating the LXRbeta-SIRT3-PGC-1alpha pathway to counter age-related muscle decline.

Experiments in miceMuscle