There are 8 papers on Creutzfeldt-Jakob disease in aging research: 2 observational studies in people, 1 in animals, 1 in cells, 4 reviews.
8 papers study it6 more mention it2 findings
See all 14 papers on Creutzfeldt-Jakob disease
“we observed a reduction in the amount of mtDNA copy in both AD and CJD”
- Humans2
- Animals1
- Cells1
Effects
1Age-related molecular signatures
upin humans1
1 study
Age-related molecular signatures
upin humans1
Creutzfeldt-Jakob disease is linked with higher age-related molecular signatures in human victims of Creutzfeldt-Jakob disease.
“We confirmed this finding in mouse models and human victims of Creutzfeldt-Jakob disease.”
Humansin human victims of Creutzfeldt-Jakob disease
Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions
Communications biology
Associations
1Mitochondrial DNA copy number
downin humans1
1 study
Mitochondrial DNA copy number
downin humans1
Creutzfeldt-Jakob disease is associated with mitochondrial DNA copy number in humans (post-mortem brain).
“we observed a reduction in the amount of mtDNA copy in both AD and CJD”
Humanspost-mortem brainbrain
Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains
Acta neuropathologica communications
Trial sponsors
1 trialPhase 3246 people