Brain MRI

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Cerebral Circulation - Cognition and BehaviorHumans

Disadvantaged neighborhoods tie to lower brain vascular function

In 132 older adults, greater neighborhood deprivation was associated with lower whole-brain cerebrovascular reactivity, independent of traditional…In 132 older adults, greater neighborhood deprivation was associated with lower whole-brain cerebrovascular reactivity, independent of traditional vascular risks and Alzheimer's pathology.

medRxivHumansPreprint

Brain small vessel disease links to stroke and mortality risk

Compared with a zero score, participants with cerebral small vessel disease scores of 1 and 2 had hazard ratios of 1.48 and 1.52 for adverse events.Compared with a zero score, participants with cerebral small vessel disease scores of 1 and 2 had hazard ratios of 1.48 and 1.52 for adverse events.

Research SquareIn silicoPreprint

Simple anatomical features match complex AI models on brain MRIs

Across about 80,000 human participants, simple anatomical measurements performed as well as complex AI models while improved pretraining boosted…Across about 80,000 human participants, simple anatomical measurements performed as well as complex AI models while improved pretraining boosted biological age estimation.

medRxivIn silicoPreprint

Automated tool counts teeth from routine brain MRI

The model counted teeth with a mean absolute error of 1.96 and matched manual associations with cognitive scores in a 233-person cohort.The model counted teeth with a mean absolute error of 1.96 and matched manual associations with cognitive scores in a 233-person cohort.

Human Brain MappingHumans

White matter changes accelerate cortical thinning more in men

Across nine years in 104 older adults, white matter aberrations grew 7.2% annually, driving accelerated cortical thinning that was more pronounced in…Across nine years in 104 older adults, white matter aberrations grew 7.2% annually, driving accelerated cortical thinning that was more pronounced in men than women.