COL4A2
Gene1 paper2 findingsHGNC 2203NCBI Gene 1284Taxon 9606
- Animals1
Effects
2Ca2+ sparks
upin mice1
1 study
Ca2+ sparks
upin mice1
COL4A2 increases ca2+ sparks in mice.
AnimalsCol4a2+/G646D micecerebral pial artery smooth muscle cells
Col4a2 mutation disrupts cerebral artery function in aged mice · bioRxiv · 1 Oct 2026 · Preprint
Pressure-induced myogenic tone
downin mice1
1 study
Pressure-induced myogenic tone
downin mice1
COL4A2 impairs pressure-induced myogenic tone in mice.
Animalsheterozygous Col4a2+/G646D mutationcerebral pial artery
Col4a2 mutation disrupts cerebral artery function in aged mice · bioRxiv · 1 Oct 2026 · Preprint
Latest
1Col4a2 mutation disrupts cerebral artery function in aged mice
In 12-month-old Col4a2 mutant mice, cerebral pial arteries showed impaired myogenic tone driven by PKA-dependent remodeling of ryanodine receptor…In 12-month-old Col4a2 mutant mice, cerebral pial arteries showed impaired myogenic tone driven by PKA-dependent remodeling of ryanodine receptor clusters.