Cartilage damage
4 papers study it72 more mention it
- Human trial1
- Humans1
- Cells1
Trial sponsors
1 trialPhase 458 people
University of California, San Francisco
1 trialPhase 420 people
South China Research Center for Stem Cell and Regenerative Medicine
1 trialPhase 1/220 people
Steadman Philippon Research Institute
1 trialPhase 1/21 person
Latest
19 papers in 12 monthsInternational Immunopharmacology
The role of immune aging in rheumatoid arthritis and its clinical and therapeutic significance
ReviewImmune response
Arthritis & Rheumatology
MDL-800-induced SIRT6 activation decreases age-associated osteoarthritis in mice
Experiments in miceOsteoarthritis
Science Advances
Adipose-cartilage communication via EV-Mito-mtDNA signaling promotes osteoarthritis progression
Experiments in micecGAS–STING signaling
Osteoarthritis and Cartilage
TL1A(TNFSF15)-ENO1 axis promotes osteoarthritis by disrupting redox homeostasis via the PI3K/AKT pathway
Experiments in micePI3K–AKT signaling
Advanced Science
Targeting NSUN2-Mediated m⁵C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis
Experiments in miceCellular senescence
International Immunopharmacology
Nox4 mediates chondrocyte senescence and cartilage degradation in post-traumatic osteoarthritis via the ROS/p38MAPK signaling pathway
Experiments in micep38 MAPK signaling
Biomolecules & Therapeutics
Ferroptosis-Driven Senescence Loop as a Central Amplifier of Osteoarthritis Progression
ReviewFerroptosis