3 papers1 finding
KL
downin mice1
KL protects against calcification in mice.
“Kl deficiency sensitizes the CP to age-related calcification prior to overt structural decline”
Animalsshown by CP-specific deletion (KlΔCP)
Distinct effects of aging and klotho deletion on the choroid plexus
GeroScience25 Mar 2026
Company1 trialPhase 4360 people
Radboud University Medical Center
1 trialPhase 3150 people
Higher calcium in the main artery was linked to cardiovascular death, heart attack or heart failure admission in 3,580 patients followed for a median 52 months.Higher calcium in the main artery was linked to cardiovascular death, heart attack or heart failure admission in 3,580 patients followed for a median 52 months.
People in the lowest parental income fifth had 1.43 times the odds of moderate-to-severe heart artery disease compared with the highest fifth.People in the lowest parental income fifth had 1.43 times the odds of moderate-to-severe heart artery disease compared with the highest fifth.