Barth Syndrome
- Animals2
Trial sponsors
Company2 trialsPhase 460 people
Latest
1 in 12 monthsScientific Reports
Tafazzin-deficient zebrafish display mitochondrial dysfunction, neutropenia, and metabolic defects without myopathy
Experiments in zebrafishAmino acid metabolism
Research Square
Tafazzin-Deficient Zebrafish Display Mitochondrial Dysfunction, Neutropenia, and Metabolic Defects Without Myopathy
Preprint: experiments in zebrafishAmino acid metabolism
International Journal of Molecular Sciences
A Barth Syndrome Patient-Derived D75H Point Mutation in TAFAZZIN Drives Progressive Cardiomyopathy in Mice
Experiments in miceMechanisms
PLOS One
A novel panel of Drosophila TAFAZZIN mutants in distinct genetic backgrounds as a resource for therapeutic testing
Experiments in model organismsInterventions
Disease Models & Mechanisms
Stimulating the sir2-spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome
Experiments in model organismsInterventions
bioRxiv
Stimulating the sir2-pgc-1ɑ axis rescues exercise capacity and mitochondrial respiration in Drosophila tafazzin mutants
Preprint: experiments in model organismsInterventions