1 paper
Company1 trialPhase 3695 people
Federal University of São Paulo
1 trialPhase 230 people
University of Kansas Medical Center
1 trialPhase 230 people
Maastricht University Medical Center
1 trialPhase 1/229 people
1 trialEarly phase 140 people
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Experiments with lab-grown liver and muscle cells linked statin exposure to lower levels of insulin-like growth factor-1, a growth signal.Experiments with lab-grown liver and muscle cells linked statin exposure to lower levels of insulin-like growth factor-1, a growth signal.
In 5,774 adults followed for an average of 4.7 years, carrying two APOE ε4 alleles and female sex were linked to faster hippocampal shrinkage.In 5,774 adults followed for an average of 4.7 years, carrying two APOE ε4 alleles and female sex were linked to faster hippocampal shrinkage.
In a mouse model of lung cancer, restricting food before tumour induction preserved lean mass and prolonged survival where targeting individual candidate factors failed.In a mouse model of lung cancer, restricting food before tumour induction preserved lean mass and prolonged survival where targeting individual candidate factors failed.
Overfeeding young mice damaged gut microbes, impaired muscle cell energy production, and worsened age-related muscle wasting in later life.Overfeeding young mice damaged gut microbes, impaired muscle cell energy production, and worsened age-related muscle wasting in later life.
An observational study of 292 people under 65 linked two positive Alzheimer’s-related spinal-fluid tests to earlier and more extensive thinning.An observational study of 292 people under 65 linked two positive Alzheimer’s-related spinal-fluid tests to earlier and more extensive thinning.