Alzheimer's disease and other dementias

Disease1 paper1 finding

  • In silico1

Associations

1

High fasting plasma glucose

upin humans1

1 study
  1. high fasting plasma glucose raises the risk of Alzheimer's disease and other dementias in humans.

    Humans

    Trends and Projections of Alzheimer's Disease and Other Dementias in East Asia: Three Decades of Epidemiological Analysis (1990-2023) with Forecasts to 2050 · Neuroepidemiology · 29 Sep 2026

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Research SquareIn silicoPreprint

Count-based records top foundation models for dementia risk

At 36 months before diagnosis, count-based models reached an AUROC of 0.738 compared with 0.719 for pretrained foundation models in All of Us records.At 36 months before diagnosis, count-based models reached an AUROC of 0.738 compared with 0.719 for pretrained foundation models in All of Us records.

Kidney MedicineHumans

Neighborhood disadvantage links to dementia in kidney failure

Among older dialysis patients, living in highly disadvantaged neighborhoods was linked to adjusted hazard ratios of 1.09 for dementia and 1.25 for…Among older dialysis patients, living in highly disadvantaged neighborhoods was linked to adjusted hazard ratios of 1.09 for dementia and 1.25 for Alzheimer's disease.

medRxivHumansPreprint

Tablet test detects cognitive impairment in older Ugandans

In 563 older adults in Uganda, a brief tablet-based composite score discriminated objective cognitive impairment with a c-statistic of 0.77.In 563 older adults in Uganda, a brief tablet-based composite score discriminated objective cognitive impairment with a c-statistic of 0.77.

Frontiers in Aging NeuroscienceHumans

COVID-19 tied to higher dementia risk in older adults with diabetes

Older adults had an overall dementia hazard ratio of 1.51 after documented infection compared with matched uninfected peers across up to six years of…Older adults had an overall dementia hazard ratio of 1.51 after documented infection compared with matched uninfected peers across up to six years of follow-up.

Alzheimer's & DementiaHumans

Comprehensive exposome score predicts incident dementia risk

An exposome-based model reached an AUC of 0.718 for incident dementia, outperforming demographics and APOE status alone at 0.678 over 15.3 years of…An exposome-based model reached an AUC of 0.718 for incident dementia, outperforming demographics and APOE status alone at 0.678 over 15.3 years of follow-up.