2 papers
In an animal experiment, mice whose ovaries had been removed showed worse osteoporosis and anxiety- and depression-like behaviour after eight weeks of chronic stress.In an animal experiment, mice whose ovaries had been removed showed worse osteoporosis and anxiety- and depression-like behaviour after eight weeks of chronic stress.
Targeting hydrogen sulfide generation to endothelial mitochondria mitigated senescence programs and reversed vascular remodeling in aged mice.Targeting hydrogen sulfide generation to endothelial mitochondria mitigated senescence programs and reversed vascular remodeling in aged mice.
In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.