Vascular aging

Biomarker

3 papers1 finding

  • Humans2

Associations

1

Major adverse cardiovascular events

upin humans1HR 5.19

1 study
  1. Vascular aging raises the risk of major adverse cardiovascular events in humans (HR: 5.19 vs 1.82).

    “this association being more pronounced in participants exhibiting vascular aging (HR: 5.19 vs 1.82; P for interaction = 0.039)”

    Humansadvanced CKM syndrome with vascular agingmedian follow-up of 5.42 yearsn = 2,584

    Vascular Aging, Cardiovascular-Kidney-Metabolic Syndrome, and Cardiovascular Risk: The Northern Shanghai Study

    JACC. Advances29 Oct 2025

Funding

33 grants since 2017

Japan Society for the Promotion of ScienceJP¥68.5mAmerican Heart AssociationUS$869.6kCanadian Space AgencyCA$3.2m

Latest

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Geriatrics & Gerontology International

Muscle wasting worsened artery damage in immobilised mice

In experiments, male mice with immobilised hindlimbs developed more calcium build-up and larger aneurysms after 42 days than mice with induced aneurysms alone.In experiments, male mice with immobilised hindlimbs developed more calcium build-up and larger aneurysms after 42 days than mice with induced aneurysms alone.

Experiments in male C57BL/6J mice, 42 days, against mice with AAA aloneMuscle

Limit: Reciprocal effects of vascular pathology on muscle atrophy were not measured

中国科学与技术学报

Stiffening arteries linked to tooth loss in older adults

Adults with moderate and high increases in estimated arterial stiffness had odds ratios of 1.32 and 1.78 for tooth loss compared with a low-stable group.Adults with moderate and high increases in estimated arterial stiffness had odds ratios of 1.32 and 1.78 for tooth loss compared with a low-stable group.

Cohort study of 10,245 peopleTooth loss
Aging Cell

Time-restricted eating slows blood vessel aging in animals

In an animal experiment, limiting daily eating hours altered gut bacteria and boosted acetic acid, easing high blood pressure and artery stiffness.In an animal experiment, limiting daily eating hours altered gut bacteria and boosted acetic acid, easing high blood pressure and artery stiffness.

Experiments in animalsDietary restriction