Synaptic proteins

2 papers

Animals2

Latest

32 in 12 months

Neurobiology of Disease10 Oct

Spinal fluid proteins linked to Alzheimer’s markers

An observational study of older adults at elevated familial risk linked spinal fluid proteins to a rising Alzheimer’s marker over up to 12 years.An observational study of older adults at elevated familial risk linked spinal fluid proteins to a rising Alzheimer’s marker over up to 12 years.

Cohort study in peopleMechanisms

bioRxiv2 Oct

Voluntary running shows limited neuroprotection in mice

In 5xFAD mice, 16 weeks of voluntary wheel running altered fat tissue but produced modest hippocampal changes and failed to improve amyloid pathology or memory.In 5xFAD mice, 16 weeks of voluntary wheel running altered fat tissue but produced modest hippocampal changes and failed to improve amyloid pathology or memory.

Preprint: experiments in miceInterventions

medRxiv24 Sep

Plasma Proteomic Mediators of the Association Between Early-Pregnancy Psychosocial Stress and Cardiovascular Health 2 to 7 Years After Delivery: The nuMoM2b-HHS Study

Preprint: cohort study of 1,662 peopleMechanisms

Journal of Microbiology and Biotechnology22 Sep

Dietary Magnolia kobus DC. Attenuates Age-Associated Hippocampal Alterations in Mice in Association with Modulation of Iron Metabolism- and Ferroptosis-Related Markers

Experiments in miceInterventions

CNS Neuroscience & Therapeutics10 Sep

Sleep Deprivation Induces Glial Dysfunction, Synaptic Loss, Metabolic Imbalance, and Cognitive Impairment in 12-Month-Old Mice: Protective Effects of D30

Experiments in miceCognitive impairment

Journal of Visualized Experiments9 Sep

Effects of Qi-fu-yin on Improving Cognitive Impairment and Reducing Cellular Senescence in the Brains of 5xFAD Mice

Experiments in miceMild cognitive impairment

Pharmacological Research3 Sep

Spectinabilin mitigates Aβ-associated proteotoxic stress and preserves synaptic protein expression in cellular and Caenorhabditis elegans models

Experiments in mouse cellsInterventions

bioRxiv31 Aug

Cerebrospinal fluid YWHAG:NPTX2 ratio predicts clinical severity and future phenoconversion in frontotemporal lobar degeneration

Preprint: cohort study in peopleBiomarkers

Research Square27 Aug

Low-dose lithium prevents age-dependent metabolic stress–driven alzheimer’s disease–like pathology through restoration of the NAMPT–NAD⁺–SIRT1–AMPK–TFEB metabolic resilience network

Preprint: experiments in miceLithium

bioRxiv27 Aug

CSF complement proteins are associated with early tau pathology and synaptic damage in an asymptomatic population at risk of Alzheimer's disease

Preprint: cohort study of 708 peopleComplement system