Short telomeres
3 papers4 findings
- Human trial1
- Humans2
Associations
4Common carotid intima-media thickness
upin humans1OR 2.373
1 study
Common carotid intima-media thickness
upin humans1OR 2.373
Common carotid intima-media thickness raises the risk of short telomeres in humans (OR 2.373, 95%CI 1.4962-3.764).
“the highest IMT-CC group showed a twofold greater risk of short telomeres compared to the reference group (<0.7mm; OR 2.373, 95%CI 1.4962-3.764)”
Humansin coronary heart disease patients, compared to IMT-CC <0.7mmn = 903
Telomere length is associated with arterial damage in the CORDIOPREV study
Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis2 Dec 2025
Ultra-processed foods
upin humans1OR 1.82
1 study
Ultra-processed foods
upin humans1OR 1.82
Ultra-processed foods raise the risk of short telomeres in humans (adjusted OR: 1.82; 95% CI: 1.05, 3.22).
“Those participants with the highest UPF consumption had almost twice the odds of having short telomeres compared with those with the lowest consumption (adjusted OR: 1.82; 95% CI: 1.05, 3.22”
Humanshighest vs. lowest UPF consumption quartilesalivan = 886
The American journal of clinical nutrition1 Jun 2020
Dietary inflammatory index
upin humans1OR 1.8
1 study
Dietary inflammatory index
upin humans1OR 1.8
Dietary inflammatory index is associated with short telomeres in humans (OR 1.80, 95% CI: 1.03, 3.17).
“multivariable-adjusted OR for short telomeres (z score ≤20th percentile) was 1.80 (95% CI: 1.03, 3.17) in a comparison between the highest (proinflammatory) and the lowest (anti-inflammatory) DII tertiles.”
Human trialhigh cardiovascular disease riskleukocytesbaselinen = 520
The American journal of clinical nutrition9 Sep 2015
Myocardial infarction
upin humans1
1 study
Myocardial infarction
upin humans1
Short telomeres raise the risk of myocardial infarction in humans (2.8- to 3.2-fold).
“the risk of myocardial infarction was increased between 2.8- and 3.2-fold (P<0.0001) in subjects with shorter than average telomeres.”
Humansleukocytes
White cell telomere length and risk of premature myocardial infarction
Arteriosclerosis, thrombosis, and vascular biology20 Mar 2003
Funding
2 grants since 2025National Institute on AgingUS$4.2mNational Institute of Diabetes and Digestive and Kidney DiseasesUS$150k
CLINICAL SIGNIFICANCE OF SOMATIC MOSAIC STATES IN THE CONTEXT OF SHORT TELOMERES
National Institute of Diabetes and Digestive and Kidney DiseasesMayo Clinic RochesterUS$150k2025–2027
Assessing therapeutic intervention of short telomere syndromes
National Institute on AgingNational Institute on AgingUS$1.1m