Senescent BMSCs

2 papers

Animals2

Latest

9 in 12 months

Biomaterials Advances31 Aug

Tannic acid-derived nanocarbon promotes angiogenesis by restoring the paracrine activity of senescent BMSCs through the Lama2/integrin α3β1/PI3K/AKT axis

Experiments in ratsInterventions

Regenerative Therapy4 Aug

Punicalagin alleviates senile osteoporosis by inhibiting the senescence of bone mesenchymal stem cells via NRF2/HO-1 pathway

Experiments in rat cellsOsteoporosis

Nanomedicine23 Mar

SHED-derived exosomes ameliorate age-related osteoporosis by activating mitophagy in senescent bone marrow mesenchymal stem cells

Experiments in miceOsteoporosis

Advanced Science28 Jan

Co-Treatment With rhBMP-2 and Rapamycin Modulates Osteogenesis-Adipogenesis Balance to Enhance Aged Bone Regeneration

Experiments in animalsRapamycin

Biomaterials16 Jan

Iron oxide nanoparticles-driven mitochondrial renewal rejuvenates the aged bone marrow niche

Experiments in animalsBones and joints

Advanced Science8 Jan

ROS Activated NETosis of Bone Marrow CD55⁺ Intermediate Mature Neutrophils Through HIF1α-PADI4 Pathway to Initiate Bone Aging

Experiments in miceOxidative stress and ROS signalling

Stem Cell Research & Therapy29 Dec

Senescence of bone marrow mesenchymal stromal cells: a narrative review of mechanisms, functional consequences, and rejuvenation strategies for age-related disorders

ReviewCellular senescence

Stem Cell Research & Therapy28 Nov

Senescent bone marrow mesenchymal stem cells exacerbate subchondral bone sclerosis and osteoarthritis via the senescence-associated secretory phenotype

Experiments in miceOsteoarthritis

Advanced Science7 Nov

Steap4 Promotes Senile Osteoporosis via Fe²⁺-ROS/C/EBPβ Feedback-Driven Ferroptosis and Adipogenesis in Senescent BMSCs

Experiments in miceFerroptosis

Phytomedicine4 Nov

Kaempferol ameliorates BMSCs senescence in postmenopausal osteoporosis by targeting Sp1 to activate FUNDC1-mediated mitophagy

Experiments in ratsPostmenopausal osteoporosis