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Frontiers in NeurologyHumans

Osteocalcin links brain volume to cognition in osteoporosis

In people with osteoporosis, higher undercarboxylated osteocalcin correlated with greater medial prefrontal cortex volume, which predicted one-year…In people with osteoporosis, higher undercarboxylated osteocalcin correlated with greater medial prefrontal cortex volume, which predicted one-year cognitive decline with an AUC of 0.84.