Senescence biomarker expression

1 paper1 finding

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L-carnosine

downin mice1

1 study

L-carnosine decreases senescence biomarker expression in mice.
“L-carnosine reduced the abundance of 4-HNE-modified proteins and blunted the expression of senescence biomarkers CDKN1A (p21Cip1), PLAUR, BCL2L1, and BCL2L2.”
Animalsobese C57BL/6J mice; CDKN1A, PLAUR, BCL2L1 and BCL2L2 expressionvisceral adipose tissue
Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells
Aging cell11 Oct 2024

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