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Robustness

Papers on robustness

13,960 papers914 new in 30 days

Tuesday, November 3

Journal of Nanobiotechnology

Immune-cell particles ease bone and muscle decline in aged mice

Experiments in naturally aged mice found benefits from immune-cell particles, with aerobic exercise further improving selected tissue-rebuilding and movement measures.Experiments in naturally aged mice found benefits from immune-cell particles, with aerobic exercise further improving selected tissue-rebuilding and movement measures.

Mouse studyMuscle
Paper
medRxiv

Metformin linked to lower dementia risk in US health records

Metformin’s dementia hazard ratio—a comparison of risk over time—was 0.90 versus sulfonylurea diabetes drugs; the range of likely values included no difference.Metformin’s dementia hazard ratio—a comparison of risk over time—was 0.90 versus sulfonylurea diabetes drugs; the range of likely values included no difference.

Brain cross-sections sit beside matching groups of upright people, with fuller dark blue-green folds and wider gaps in the smaller gray section.
Preprint: cohort studyDementia
Paper
BMC Geriatrics

Light exercise with blood flow restriction may aid strength and memory

An eight-week randomized trial in 36 oldest-old adults found favorable changes versus no exercise, but limited evidence of added benefit over matched light exercise.An eight-week randomized trial in 36 oldest-old adults found favorable changes versus no exercise, but limited evidence of added benefit over matched light exercise.

Randomized trial · 36 peopleInterventions
Paper
NPJ Aging

Faster brain aging linked to death and disease across the body

An observational analysis of brain scans from over 60,000 UK Biobank participants linked accelerated brain aging to death and diseases affecting multiple organ systems.An observational analysis of brain scans from over 60,000 UK Biobank participants linked accelerated brain aging to death and diseases affecting multiple organ systems.

Cohort studyBiomarkers
Paper
Nature Nanotechnology

Tiny fat-based particles delivered RNA to mouse brains

In mouse experiments, the particles delivered gene-editing components to the brain and carried RNA that reduced radiation-induced brain injury.In mouse experiments, the particles delivered gene-editing components to the brain and carried RNA that reduced radiation-induced brain injury.

Mouse studyInterventions
Paper
Ophthalmology

Algorithm detected glaucoma in older adults’ eye photos

The algorithm detected 70.6% of affected eyes while correctly classifying 95% of eyes without glaucoma in an external population-based validation.The algorithm detected 70.6% of affected eyes while correctly classifying 95% of eyes without glaucoma in an external population-based validation.

Cohort · 9,837 peopleBiomarkers
Paper

Monday, November 2

medRxiv

Physical stress burden linked to cancer before age 50

A case-control study estimated that physical stress burden accounted for 17.0% of the association between an environmental exposure score and exposure-related cancers…A case-control study estimated that physical stress burden accounted for 17.0% of the association between an environmental exposure score and exposure-related cancers diagnosed before 50.

A group of upright, faceless people stands between orderly pale cells and irregular dark cells with enlarged nuclei.
Preprint: case-control · 7,550 peopleMechanisms
Paper