Ribosomal protein gene expression
2 papers2 findings
- Humans1
- Cells1
Upstream
1ETS1
upin human cells1
1 study
ETS1
upin human cells1
ETS1 increases ribosomal protein gene expression in human cells.
“ETS1 knockdown reduces RPG expression”
CellsShown by ETS1 knockdownHuman dermal fibroblasts and IMR-90 embryonic lung fibroblasts
ETS1 acts as a regulator of human healthy aging via decreasing ribosomal activity
Science advances27 Apr 2022
Associations
1ETS1
upin humans1
1 study
ETS1
upin humans1
ETS1 is associated with ribosomal protein gene expression in humans.
“ETS1 (ETS proto-oncogene 1), a transcription factor down-regulated in LLIs and positively coexpressed with most ribosomal protein genes (RPGs).”
HumansLong-lived individuals
ETS1 acts as a regulator of human healthy aging via decreasing ribosomal activity
Science advances27 Apr 2022
Latest
3 in 12 monthsAdvanced Biology
Single-Cell Analyses Reveal Dysregulation of Ribosomal Protein Genes During Hematopoietic Stem and Progenitor Cell Aging
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Preserved mitochondrial ribosomal protein gene expression marks a youthful transcriptional state in Chinese nonagenarians and centenarians
Case-control study of 940 peopleMitochondrion
bioRxiv
Rpl12 paralog dependent TOR-signaling controls the expression of ribosome preservation factor Stm1
Preprint: experiments in yeastmTOR signalling
EMBO Reports
Ageing-associated long non-coding RNA extends lifespan and reduces translation in non-dividing cells
Experiments in model organismsMechanisms
Science Advances
ETS1 acts as a regulator of human healthy aging via decreasing ribosomal activity
Cross-sectional study of 185 peopleMechanisms