pTau-217
Biomarker2 papers3 findings
- Humans1
- Animals1
Effects
2Oxyhemoglobin
upin humans1downin humans1
1 study
Oxyhemoglobin
upin humans1downin humans1
pTau-217 increases oxyhemoglobin in humans.
Humansduring Stroop congruent trialsprefrontal cortex
Prefrontal hemodynamic alterations during resting state and stroop interference in cognitively healthy older adults with high plasma pTau-217 levels · Neuroimage. Reports · 17 Sep 2026
pTau-217 decreases oxyhemoglobin in humans.
Humansduring eyes-open restprefrontal cortex
Prefrontal hemodynamic alterations during resting state and stroop interference in cognitively healthy older adults with high plasma pTau-217 levels · Neuroimage. Reports · 17 Sep 2026
Cognitive function
downin humans1
1 study
Cognitive function
downin humans1
pTau-217 impairs cognitive function in humans.
Humanshigh vs low tertile pTau-217
Prefrontal hemodynamic alterations during resting state and stroop interference in cognitively healthy older adults with high plasma pTau-217 levels · Neuroimage. Reports · 17 Sep 2026
Latest
3Plasma tau-217 levels rise early in tuberous sclerosis complex
Log2 ptau-217 concentrations were significantly higher in 63 people with tuberous sclerosis complex than in 116 cognitively unimpaired controls (p <…Log2 ptau-217 concentrations were significantly higher in 63 people with tuberous sclerosis complex than in 116 cognitively unimpaired controls (p < 0.0001).
App knock-in mice display age-dependent Alzheimer's pathology
In a study of App SAA knock-in mice from 4 to 19 months, animals developed progressive amyloid pathology, neuroinflammation, biomarker shifts, and…In a study of App SAA knock-in mice from 4 to 19 months, animals developed progressive amyloid pathology, neuroinflammation, biomarker shifts, and synaptic loss.