Plasma pTau-217
Biomarker1 paper1 finding
- Animals1
Upstream
1APP
upin mice1
1 study
APP
upin mice1
APP increases plasma pTau-217 in mice.
Animals
App knock-in mice display age-dependent Alzheimer's pathology · bioRxiv : the preprint server for biology · 10 Sep 2026 · Preprint
Latest
3Plasma tau-217 levels rise early in tuberous sclerosis complex
Log2 ptau-217 concentrations were significantly higher in 63 people with tuberous sclerosis complex than in 116 cognitively unimpaired controls (p <…Log2 ptau-217 concentrations were significantly higher in 63 people with tuberous sclerosis complex than in 116 cognitively unimpaired controls (p < 0.0001).
App knock-in mice display age-dependent Alzheimer's pathology
In a study of App SAA knock-in mice from 4 to 19 months, animals developed progressive amyloid pathology, neuroinflammation, biomarker shifts, and…In a study of App SAA knock-in mice from 4 to 19 months, animals developed progressive amyloid pathology, neuroinflammation, biomarker shifts, and synaptic loss.