Papers on prostaglandin

264 papers9 new in 30 days

Tuesday, November 3

Nutrition ResearchNov 3

Potential Vascular Mechanisms Underlying the Antihypertensive Effects of Blueberries: A Narrative Review

ReviewInterventions

Paper

Sunday, November 1

Theoretical and Natural ScienceNov 1

Aspirin: Classical Molecular Pharmacology, Off-Label; Repurposing Potentials and Benefit-Risks

ReviewAspirin

Paper

Tuesday, October 27

AntioxidantsOct 27

The Senescence-Malignancy Axis: An Inflammaging Perspective

The role of ROS in cellular senescence, immunosenescence, and SASP secretion.

ReviewCellular senescence

Paper

International Journal of Molecular SciencesOct 27

EP2 and EP4 in Alzheimer's Disease: Cell-Dependent Signalling and Implications for Selective Targeting

EP2 and EP4 both activate Gs–cAMP signalling but differ in G-protein coupling and receptor trafficking.

ReviewAlzheimer's disease

Paper

Monday, October 26

ESC Congress 2026 AbstractOct 26

A chemical signal lowers energy output in blood vessel muscle cells

In experiments with blood vessel muscle cells, the signal also promoted an inflammatory state and impaired mitochondria, the cells’ energy-producing structures.In experiments with blood vessel muscle cells, the signal also promoted an inflammatory state and impaired mitochondria, the cells’ energy-producing structures.

Blood vessel muscle cells contain intact folded mitochondria beside gray cells with fragmented mitochondria and dark clusters, with a mouse above.

Animal cell studyMechanisms

Paper

Byulleten Nauki I PraktikiOct 26

The role of endothelial dysfunction in the development of chronic heart failure in the elderly

ReviewMechanisms

Paper

Sunday, October 25

Redox BiologyOct 25

Benzene exposure in relation to the development of glycemic dysregulation and type 2 diabetes mediated by oxidative stress and aggravated by inflammation in a repeated-measure prospective cohort study of Chinese adults

Cohort study of 3,422 peopleType 2 diabetes

Paper

Sunday, October 11

Journal of Orthopaedic SurgeryOct 11

Glaucoma eye-drop groups differed in osteoporosis risk

Osteoporosis was diagnosed in 13.3% of patients prescribed drops such as latanoprost, compared with 8.9% prescribed drops such as pilocarpine.Osteoporosis was diagnosed in 13.3% of patients prescribed drops such as latanoprost, compared with 8.9% prescribed drops such as pilocarpine.

A large dark blue-green thigh bone with sparse internal struts stands beside a smaller, denser gray bone, each near an eye with a droplet above it.

Cohort study of 6,743 peoplePrimary open-angle glaucoma

Paper

Journal of Inflammation ResearchOct 11

Hydroxygenkwanin Identified in Rehmanniae Radix Praeparata-Corni Fructus Ameliorates Postmenopausal Osteoporosis via Modulation of the AGE-RAGE Signaling Pathway

Figure from Journal of Inflammation Research

Experiments in ratsPostmenopausal osteoporosis

Paper

Saturday, October 3

EMBO Molecular MedicineOct 3

Prostaglandin E2 drives cellular senescence and scar fibrosis after cesarean section in mice

Blocking the prostaglandin E2 pathway or targeting cellular senescence reduces uterine scarring and improves tissue repair in mouse models of cesarean defects.Blocking the prostaglandin E2 pathway or targeting cellular senescence reduces uterine scarring and improves tissue repair in mouse models of cesarean defects.

Experiments in miceCellular senescence

Paper

Saturday, September 26

bioRxivSep 26

A Community-Driven Single-Cell PBMC Reference Integrating Landmark Datasets Spanning Health and Disease

Preprint: computational studyAI & data

Paper

Wednesday, September 23

Aging CellSep 23

Transplantation of Elderly Human Gut Microbiota Into Pigs Reprograms Intestinal Barrier Function, Plasma Metabolome, and Gut Mucosal Transcriptomic Landscape

Experimental design and effects of antibiotic treatment and fecal microbiota transplantation (FMT) on gut microbial diversity in pigs.

Experiments in pigsFecal microbiota transplantation

Paper

Sunday, September 6

Environment InternationalSep 6

Cross-sectional and longitudinal relationships between exposure to polychlorinated biphenyls and predicted 10-year atherosclerotic cardiovascular disease risk: Integrated epidemiological and bioinformatics analysis

Cohort study in peopleAtherosclerotic cardiovascular disease

Paper

Wednesday, August 26

CellsAug 26

NCOA4-Mediated Ferritinophagy Contributes to Iron Overload-Driven Ferroptosis of Senescent Myoblasts in Mice

Iron overload and ferroptosis occurred in D-gal-induced senescent myoblasts.

Experiments in cellsFerroptosis

Paper

Saturday, August 22

Aging CellAug 22

Piezo1 Activation Rescues Anabolic Response to Mechanical Loading in Aged Bone via Connexin 43 Hemichannels

Aging blunts the anabolic responses of tibial bone to mechanical loading.

Experiments in micePIEZO1

Paper

Friday, August 7

bioRxivAug 7

Restoration of Capacity to Build Muscle Strength in Geriatric Mice by Inhibition of the Gerozyme 15-Prostaglandin Dehydrogenase

Preprint: experiments in miceMuscle

Paper

Thursday, July 30

American Journal of Physiology Regulatory, Integrative and Comparative PhysiologyJul 30

The impact of age and exercise training on endothelial-mediated mechanisms of vasodilation during passive leg movement in males

Non-randomized trial in peopleExercise

Paper

Thursday, July 23

Discovery MedicineJul 23

Unlocking Bone Health: How Syringin Inhibits Osteoclasts via PTGS1 in Postmenopausal Osteoporosis

Experiments in ratsPostmenopausal osteoporosis

Paper

Friday, July 17

Molecular BiomedicineJul 17

Blocking a signal gives human immune cells tumor-linked traits

In laboratory experiments, blocking a signal for 24 hours gave human immune cells features resembling those of immune cells found in tumors.In laboratory experiments, blocking a signal for 24 hours gave human immune cells features resembling those of immune cells found in tumors.

Human cell studyBlood and immune system

Paper

Thursday, July 16

ScienceJul 16

Tidying up aging organs

CommentaryMechanisms

Paper

ScienceJul 16

Restored clearance of senescent neutrophils by tissue-resident macrophages limits organ aging

Experiments in miceCellular senescence

Paper

Friday, July 10

BiomedicinesJul 10

Clinical Determinants and Bone Metabolic Correlates of 24-h Urinary PGE2 and PGEM Excretion in Chinese Adults: A Multicenter Cross-Sectional Study

Cross-sectional study of 737 peoplePopulations

Paper

Thursday, June 25

Aging CellJun 25

Removing an enzyme eased kidney aging and bone loss in mice

Deleting the enzyme’s gene in kidney filtering cells reduced kidney damage and age-related bone loss in aged mice; a drug also improved kidney and bone measures.Deleting the enzyme’s gene in kidney filtering cells reduced kidney damage and age-related bone loss in aged mice; a drug also improved kidney and bone measures.

Mouse studyKidney

Paper

Monday, June 22

bioRxivJun 22

Dietary omega-6 arachidonic acid and omega-3 docosahexaenoic acid supplementation differentially impact skeletal muscle inflammaging in mice

Preprint: experiments in miceDocosahexaenoic acid

Paper

Thursday, June 18

Scientific ReportsJun 18

Translational difficulties in establishing a pharmacologically induced neurovascular uncoupling model in rats

Experiments in ratsMechanisms

Paper

Thursday, June 11

ScienceJun 11

Placental molecule helps set the timing of labor in mice

Lowering a placental molecule shortened average pregnancies to 17 days 8.4 hours, versus 18 days 18.6 hours in controls; raising it delayed birth.Lowering a placental molecule shortened average pregnancies to 17 days 8.4 hours, versus 18 days 18.6 hours in controls; raising it delayed birth.

Mouse studyInterventions

Paper

Wednesday, June 10

The Spine JournalJun 10

Aging and degeneration differ in human spinal disc chemistry

An observational comparison of tissue from 21 healthy organ donors and 40 degenerated discs found different chemical patterns in aging and degeneration.An observational comparison of tissue from 21 healthy organ donors and 40 degenerated discs found different chemical patterns in aging and degeneration.

Cross-sectional studyMechanisms

Paper

Tuesday, June 2

PNASJun 2

15-PGDH inhibition promotes muscle repair and strength recovery during GLP-1 receptor agonist-induced weight loss

Experiments in miceGLP-1 receptor agonists

Paper

Sunday, May 24

Biomedicine & PharmacotherapyMay 24

Signaling molecule improved ovarian cell function in the lab

Lab experiments using human and aged-mouse ovarian cells found greater energy production and hormone secretion after exposure to prostaglandin D2.Lab experiments using human and aged-mouse ovarian cells found greater energy production and hormone secretion after exposure to prostaglandin D2.

Cell studyReproductive system

Paper

Aging CellMay 24

Tubular Omega-3 Fatty Acid Receptor FFAR4 Deficiency Aggravated Renal Aging and Chronic Kidney Disease

Experiments in miceChronic kidney disease

Paper