A cross-sectional study of 181 people linked retinal changes to brain shrinkage, blood markers of Alzheimer's disease and cognitive impairment.A cross-sectional study of 181 people linked retinal changes to brain shrinkage, blood markers of Alzheimer's disease and cognitive impairment.
Cross-sectional study of 181 Alzheimer's patients and cognitively unimpaired controlsAlzheimer's disease
Limit: Brain changes could precede retinal changes rather than follow them
An observational study of 73,038 patients linked poorer heart blood supply to death or heart attack risk across age groups over a median 3.7 years.An observational study of 73,038 patients linked poorer heart blood supply to death or heart attack risk across age groups over a median 3.7 years.
Cohort study of patients without early revascularization, median 3.7 yearsBiomarkers
Limit: The across-age prognostic analysis excluded patients undergoing early revascularization
People with mild amyloid levels were 43% more likely to develop cognitive impairment than those with the lowest levels, around 10 years after scanning.People with mild amyloid levels were 43% more likely to develop cognitive impairment than those with the lowest levels, around 10 years after scanning.
Cohort study of 1,896 cognitively unimpaired individuals, against the lowest amyloid groupBiomarkers
Limit: The findings concern initially cognitively unimpaired people, not those with existing cognitive impairment
A cross-sectional analysis of 15,612 adults aged 55–80 screened for Alzheimer’s trials found blood marker differences between racial and ethnic groups.A cross-sectional analysis of 15,612 adults aged 55–80 screened for Alzheimer’s trials found blood marker differences between racial and ethnic groups.
In an observational study of 1,110 people, living in more deprived areas was associated with lower cognitive scores and more amyloid build-up in unimpaired brains.In an observational study of 1,110 people, living in more deprived areas was associated with lower cognitive scores and more amyloid build-up in unimpaired brains.