Phosphorylated tau
Biomarker2 papers1 finding
- Animals1
- Cells1
Interventions
1Mtdna depletion
downin human cells1
1 study
Mtdna depletion
downin human cells1
Mtdna depletion decreases phosphorylated tau in human cells.
Cellschronic mtDNA depletion (rho0)SH-SY5Y
Chronic mitochondrial DNA depletion alters MAPT splicing and increases tau levels · Journal of Alzheimer's disease : JAD · 29 Sep 2026
Latest
4Speech clocks reflect dementia phenotypes and biological aging markers
A cross-national analysis of Latin American participants connected speech age gaps to epigenetic age, brain clocks, and cognitive decline.
Science advances · Hernandez H et al.
Chronic mitochondrial DNA depletion alters MAPT splicing and increases tau levels
CellsJournal of Alzheimer's disease : JAD
Aging rhesus macaques display distinct fluid proteomic signatures of senescence and neuropathology
Plasma proteins tracked aging and amyloid pathology more closely than cerebrospinal fluid across the non-human primate lifespan.
GeroScience · Diniz GB et al.
Blood biomarkers of oxidative stress and mitochondrial dysfunction in Parkinson's disease and Alzheimer's disease
ReviewInternational review of neurobiology