Nutrition

Biomarker

2 papers

  • Humans2

Funding

95 grants since 2016

Japan Society for the Promotion of ScienceJP¥280.8mCanadian Institutes of Health Research (CIHR) Project GrantCA$2.7mAgence Nationale de la Recherche€1m

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Research Square

Short survey reliably measured physical function in older adults

The 10-question scale halved administration time compared with the 25-question version and was tested in an independent sample of 263 older adults.The 10-question scale halved administration time compared with the 25-question version and was tested in an independent sample of 263 older adults.

Preprint: study of 114 adults aged 50 years and olderBiomarkers

Limit: Ceiling scores limit discrimination among highly functioning older adults

Molecular Biomedicine

Dietary fat rebalanced brain membrane fats in mice

Docosahexaenoic acid restored brain energy function in six- and 12-month dietary experiments in female mice carrying a human gene variant linked to Alzheimer’s disease.Docosahexaenoic acid restored brain energy function in six- and 12-month dietary experiments in female mice carrying a human gene variant linked to Alzheimer’s disease.

Experiments in 37 female ApoE3/3 and ApoE4/4 knock-in mice, against control-diet ApoE4/4 miceInterventions

Limit: Lipidomics sampled cerebellum, not cortex or hippocampus, limiting claims about brain-wide membrane rebalancing