Cognition

Biomarker3 papers

  • Human trial2
  • Humans1

Funding

National Institute on AgingUS$58.2mNational Institute of Neurological Disorders and StrokeUS$10.3mNational Institute of Diabetes and Digestive and Kidney DiseasesUS$851.6k66 grants since 1997

Latest

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NPJ AgingAnimals

Protein deficiency impaired memory in aging mice

Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell…Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell signalling and increased activity linked to inflammation.

Alzheimer's Research & TherapyHumans

Gene variant linked to lower brain scan signals in women

An observational study of 101 adults aged 30–85 without cognitive impairment found no overall sex differences in a small brain region’s signals or…An observational study of 101 adults aged 30–85 without cognitive impairment found no overall sex differences in a small brain region’s signals or activity.

Journal of NeurologyHumans

Brain thinning detected before dementia in people under 65

An observational study of 292 people under 65 linked two positive Alzheimer’s-related spinal-fluid tests to earlier and more extensive thinning.An observational study of 292 people under 65 linked two positive Alzheimer’s-related spinal-fluid tests to earlier and more extensive thinning.

bioRxivHumansPreprint

Brain patterns linked to depression and markers of brain decline

An observational study of 353 adults aged 36–87 linked distinct brain patterns to later depression in younger women and blood markers of brain…An observational study of 353 adults aged 36–87 linked distinct brain patterns to later depression in younger women and blood markers of brain deterioration in older men.