Neuronal density

Biomarker2 papers1 finding

Animals1
In silico1

Upstream

1

NIPSNAP1

upin mice1

1 study

NIPSNAP1 increases neuronal density in mice.
Animalsshown by constitutive Nipsnap1 knockdownbrain
Protein deficiency impaired memory in aging mice · NPJ aging · 6 Oct 2026

Latest

11

NPJ AgingAnimals6 h

Protein deficiency impaired memory in aging mice

Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell…Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell signalling and increased activity linked to inflammation.

bioRxivAnimalsPreprint26 Sep

Cholinergic impairment in the dorsal motor nucleus of the vagus during experimental Alzheimer’s disease

Neurochemical ResearchAnimals6 Sep

Strain-Specific Cognitive and Neurobiological Vulnerabilities to Social Isolation in Late Middle-Aged Wistar, Wistar-Kyoto, and Spontaneously Hypertensive Rats

medRxivIn silicoPreprint3 Sep

External Validation of a Mathematical Model of Brain Health

Brain CommunicationsHumans28 Aug

NOR1 loss relates to inflammation and biological ageing in multiple sclerosis motor cortex

bioRxivAnimalsPreprint28 Aug

Mitochondrial dysfunction as a hallmark of brain senescence in telomerase-deficient mice

Telomerase and telomere maintenance

AAIC 2025 AbstractHumans9 Jan

Cortical integrity changes with cognition, plasma biomarkers and APOE4 status across the adult healthy lifespan

AAIC 2025 AbstractAnimals25 Dec

Neuronal reprogramming improves brain health in TgAD and aging rats

AAIC 2025 AbstractHumans24 Dec

Networks of age‐related pathologies and APOE ε4: their role in hippocampal degeneration

AAIC 2025 AbstractHumans23 Dec

Cortical integrity changes with cognition, plasma biomarkers and APOE4 status across the adult healthy lifespan