NIPSNAP1

Gene1 paper4 findings

  • Animals1

Effects

4

NAD/NADH ratio

upin mice1

1 study
  1. NIPSNAP1 increases NAD/NADH ratio in mice.

    Animalsshown by constitutive Nipsnap1 knockdownisolated brain mitochondria

    Protein deficiency impaired memory in aging mice · NPJ aging · 6 Oct 2026

NAD/NADH ratio →

Reactive oxygen species production

downin mice1

1 study
  1. NIPSNAP1 decreases reactive oxygen species production in mice.

    Animalsshown by constitutive Nipsnap1 knockdownisolated brain mitochondria

    Protein deficiency impaired memory in aging mice · NPJ aging · 6 Oct 2026

Reactive oxygen species production →

Apoptosis

downin mice1

1 study
  1. NIPSNAP1 decreases apoptosis in mice.

    Animalsshown by constitutive Nipsnap1 knockdownbrain

    Protein deficiency impaired memory in aging mice · NPJ aging · 6 Oct 2026

Apoptosis →

Neuronal density

upin mice1

1 study
  1. NIPSNAP1 increases neuronal density in mice.

    Animalsshown by constitutive Nipsnap1 knockdownbrain

    Protein deficiency impaired memory in aging mice · NPJ aging · 6 Oct 2026

Neuronal density →

Latest

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NPJ AgingAnimals

Protein deficiency impaired memory in aging mice

Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell…Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell signalling and increased activity linked to inflammation.