MCC950
Intervention1 paper2 findingsPubChem 9910393
- Cells1
Outcomes
2Cellular senescence
upin cells1
1 study
Cellular senescence
upin cells1
MCC950 induces cellular senescence in cells.
Cellsduring agingbone marrow-derived macrophages
NLRP3 inflammasome activity shifts toward regulating cell fate in aged macrophages · Bulletin of experimental biology and medicine · 28 Sep 2026
Apoptosis
downin cells1
1 study
Apoptosis
downin cells1
MCC950 decreases apoptosis in cells.
Cellsduring agingbone marrow-derived macrophages
NLRP3 inflammasome activity shifts toward regulating cell fate in aged macrophages · Bulletin of experimental biology and medicine · 28 Sep 2026
Latest
1NLRP3 inflammasome activity shifts toward regulating cell fate in aged macrophages
Inhibiting the NLRP3 inflammasome with MCC950 reduced apoptosis but increased senescence in aged bone marrow-derived macrophages.
Bulletin of experimental biology and medicine · Blagova AV et al.