Lipid accumulation
Biomarker1 paper
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13Lipid accumulation index linked to cardiometabolic multimorbidity
Each one-unit increase in log10 lipid accumulation product was associated with a cardiometabolic multimorbidity hazard ratio of 3.03 (95% CI…Each one-unit increase in log10 lipid accumulation product was associated with a cardiometabolic multimorbidity hazard ratio of 3.03 (95% CI 2.33–3.93).
Predictive value of the triglyceride-glucose index combined with novel body shape indices for cardiovascular disease: a cross-sectional study based on NHANES
Lack of dietary DHA drives harmful lipid remodeling and retinal degeneration in mice
Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.
KLF-1 regulates SKN-1 activity and longevity in worms
In germline-deficient animals, KLF-1 was required for SKN-1 activation, oxidative stress resistance, and longevity without altering skn-1 transcript…In germline-deficient animals, KLF-1 was required for SKN-1 activation, oxidative stress resistance, and longevity without altering skn-1 transcript abundance.
Lactate receptor activation reduces arterial senescence in mice
In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved…In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.