Fiber type

Biomarker

1 paper

  • Animals1

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Cell

Exercise reshaped gene activity across tissues in mice

An 8-week wheel-running experiment in mice examined 22 tissues and plasma, finding the largest gene-activity changes in skeletal muscle.An 8-week wheel-running experiment in mice examined 22 tissues and plasma, finding the largest gene-activity changes in skeletal muscle.

Experiments in mice, 8 weeksInterventions

Limit: Lifespan and health during aging were not measured

iScience

Activity and insulin resistance show opposite muscle gene links

In an observational study of 263 Finnish individuals, higher physical activity and lower insulin resistance were both linked to higher proportions of Type 1 nuclei.In an observational study of 263 Finnish individuals, higher physical activity and lower insulin resistance were both linked to higher proportions of Type 1 nuclei.

Cross-sectional study of 263 peopleInsulin resistance
Nature Aging

Cardiolipin decline drives muscle fiber shifts in mice

Deleting cardiolipin synthase in young mice induced age-like fiber shifts, while restoring its expression reversed atrophy and rescued premature mortality.Deleting cardiolipin synthase in young mice induced age-like fiber shifts, while restoring its expression reversed atrophy and rescued premature mortality.

Experiments in miceMuscle