Sports Medicine and Health Science
Exercise preconditioning prevents immobilization-induced skeletal muscle atrophy by activating Prmt1-p38/ATF2-Sesn1 signaling axis in C57BL/6J mice
Experiments in miceExercise
Papers on Factor 2
714 papers28 new in 30 days
Wednesday, February 25
Advanced Healthcare Materials
Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta-on-a-Chip Model
Experiments in miceSimvastatin
Tuesday, February 24
Chemical Biology & Drug Design
Quercetin Suppresses Inflammation and Extracellular Matrix Degradation in Knee Osteoarthritis by Inhibiting E2F2 to Modulate SFRP5/Wnt5a Signaling
Experiments in ratsQuercetin
Monday, February 23
bioRxiv
Distinct Biological and Biomechanical Features in TMJ and Knee Cartilages
Preprint: experiments in miceBones and joints
Monday, February 16
International Journal of Biological Macromolecules
ETS transcription factor 1-insulin-like growth factor 2 mRNA-binding protein 2-interferon-induced transmembrane protein 3 pathway promotes ferroptosis-driven osteoblast senescence in diabetic osteoporosis
Experiments in miceFerroptosis
Friday, February 13
Food & Nutrition Research
Estrogen promotes the angiogenesis and osteogenesis of bone marrow stromal cells via regulating ESR1/RUNX2 axis
Experiments in miceBones and joints
Thursday, February 12
JHEP Reports
3D endothelial cell scaffolds protect liver explants and exhibit therapeutic effects on liver fibrosis
Experiments in 6 miceInterventions
Wednesday, February 11
Free Radical Biology & Medicine
Nutritional activation of the Nrf2-Pth1r axis by pyrroloquinoline quinone enhances peak bone mass and potentiates teriparatide in osteoporosis
Experiments in miceTeriparatide
Frontiers in Nutrition
Efficacy of 42-month oral administration of glucoraphanin in preventing cognitive decline in individuals at elevated risk of dementia, including those with mild cognitive impairment: a randomized, double-blind, placebo-controlled pilot study
Randomized trial in 26 peopleMild cognitive impairment
Friday, February 6
International Journal of Molecular Medicine
Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling
Experiments in ratsIschemia-reperfusion injury
Thursday, February 5
Iranian Journal of Basic Medical Sciences
Artificial intelligence (AI) in academic publishing: Legitimate use, plagiarism detection, and ethical challenges
Experiments in 28 ratsInterventions
Tuesday, February 3
Monday, February 2
Journal of Pharmaceutical Innovation
Rosuvastatin-Loaded Glycerosomes as a Neuroprotective Strategy Against Hyperlipidemia-Induced Brain Dysfunction: Development, Optimization, and in vivo Evaluation
Experiments in ratsRosuvastatin
Saturday, January 31
BMC Cardiovascular Disorders
Association between MEF2A variants and ischemic stroke risk: a case-control study and two prospective cohort studies in a Chinese population
Cohort study of 4,080 peopleIschemic stroke
Wednesday, January 28
Tuesday, January 27
Biochemical Pharmacology
Diacerein protects against Ovariectomy-Induced bone loss via reversal of NRF2 epigenetic suppression
Experiments in miceBones and joints
Exploration of Neuroprotective Therapy
Stem cell-derived exosomes as neurotherapeutic agents: mechanisms of immunomodulation and neural regeneration in neurodegenerative disorders
Monday, January 26
Free Radical Biology & Medicine
Insulin-like growth factor 2 mRNA-binding Protein 2 regulates PINK1 expression through m⁶A pathway to promote mitophagy in BMSCs alleviating postmenopausal osteoporosis
Experiments in miceMitophagy
Saturday, January 24
Progress in Retinal and Eye Research
Aging, oxidative stress, and cataracts: Therapeutic prospects and translational insights into peroxiredoxin 6
Friday, January 23
bioRxiv
Precision mRNA Nanomedicine for Targeted Vascular Therapies in ARDS and Atherosclerosis
Preprint: experiments in animalsAtherosclerosis
Thursday, January 22
Sunday, January 18
Journal of Neuroimmunology
Exercise ameliorates microglial activation and cognitive impairment induced by GFAT1 knockdown after traumatic brain injury
Experiments in miceTreadmill exercise
Saturday, January 17
Nature Communications
Environmental enrichment and physical exercise prevent stress-induced social avoidance and blood-brain barrier alterations via Fgf2
Experiments in miceInterventions
Friday, January 16
Journal of Microbiology and Biotechnology
Oral intake of Heat-Killed Lactiplantibacillus plantarum Alleviates Bone Loss in an Ovariectomized Mouse Model Similarly to Live L. plantarum
Experiments in miceBone loss
Free Radical Biology & Medicine
NRF2 at the crossroads of Parkinson's disease and aging: Mechanistic insights and translational perspectives
Thursday, January 15
Respiratory Research
Runx2 acetylation enhances pulmonary inflammation in chronic obstructive pulmonary disease through activating CDK8
Case-control study in peopleChronic obstructive pulmonary disease
Tuesday, January 13
Journal of Cellular and Molecular Medicine
Electroacupuncture Pretreatment Ameliorates Perioperative Neurocognitive Disorder in Aged Mice by Inhibiting Ferroptosis Through the SIRT1/NRF2/GPX4 Pathway
Experiments in micePerioperative neurocognitive disorder
Monday, January 12
Advanced Composites and Hybrid Materials
Hybrid Bioprinting for functionally graded tissue engineering constructs with patterned and localized biochemical signals
Experiments in cellsInterventions