Papers on Factor 2

714 papers31 new in 30 days

Thursday, November 5

AJPM FocusNov 5

Risk factors associated with premature mortality from cardiovascular diseases in women: A scoping review

Systematic reviewCardiovascular disease

Paper

Wednesday, November 4

Reviews in Cardiovascular MedicineNov 4

Moderate-Dose Exercise Protects Against Heart Failure via Apelin/NLRP3 Mediated Inflammation

Exercise increases cardiac function in mice with HF.

Experiments in miceExercise

Paper

Monday, November 2

Hearing ResearchNov 2

A time-resolved single-nucleus atlas of cochlear aging reveals biphasic inflammaging and Tbx2-dependent inner hair cell maintenance

Computational studyInflammation

Paper

Sunday, November 1

Scientific ReportsNov 1

Cultural adaptation and validation of Eye Frailty Self-Check List for middle-aged and older adult in China

Cross-sectional study of 749 peopleBiomarkers

Paper

Saturday, October 31

GeroScienceOct 31

Sesaminol attenuates alcohol-induced colonic senescence in middle-aged mice: potential involvement of the AhR–Nrf2 axis

Experiments in miceInterventions

Paper

Friday, October 30

Frontiers in NutritionOct 30

Circadian-related rhythm robustness is associated with insulin sensitivity, insulin resistance, and triglycerides in healthy adults

Accepted, not yet published: cross-sectional study of 716 peopleTriglyceride

Paper

Thursday, October 29

Respiratory ResearchOct 29

Compounds reduced aging-related markers in human airway cells

Laboratory experiments in smoke-exposed airway cells from people with and without chronic obstructive pulmonary disease found that activating an antioxidant regulator…Laboratory experiments in smoke-exposed airway cells from people with and without chronic obstructive pulmonary disease found that activating an antioxidant regulator reduced senescence markers.

Human cell studyInterventions

Paper

Molecular Biology ReportsOct 29

Combined crocin and treadmill exercise regulate cardiac MicroRNA-23b, nuclear factor Erythroid 2-related factor 2, and tumor necrosis factor-alpha in experimental type 2 diabetes mellitus

Experiments in 35 ratsTreadmill exercise

Paper

Biomolecules & TherapeuticsOct 29

Nrf2 Activation Induces Fibroblast Senescence and Promotes Melanosome Accumulation in a Fibroblast-Keratinocyte Co-Culture Model

Characteristic Nrf2 expression in nevi or darkly pigmented skin and its PPI network of aging-related genes.

Experiments in cellsNRF2–KEAP1 antioxidant response

Paper

Biomolecules & TherapeuticsOct 29

Adenine Promotes Osteogenic Differentiation and Suppresses Osteoclastogenesis

Adenine activates AMPK-CREB signaling and promotes osteogenic differentiation in C2C12 cells.

Experiments in mouse cellsInterventions

Paper

Wednesday, October 28

Advanced ScienceOct 28

Protein helps bone marrow stem cells develop into bone cells

Experiments in bone marrow stem cells linked the protein to mitochondrial maintenance and signals that support blood vessel formation.Experiments in bone marrow stem cells linked the protein to mitochondrial maintenance and signals that support blood vessel formation.

Animal cell studyBones and joints

Paper

Frontiers in Cell and Developmental BiologyOct 28

Potential role of irisin-mediated oxidative stress defense in systemic diseases

Biosynthesis, tissue sources, and receptor-mediated signalling of irisin.

ReviewInterventions

Paper

Tuesday, October 27

AntioxidantsOct 27

Formononetin Protects Osteoblasts Against Oxidative Stress and Attenuates Ovariectomy-Induced Bone Loss in Association with MAPK/AP-1 and NRF2 Signaling

FMN attenuates OVX-induced trabecular bone loss and systemic oxidative stress in mice.

Experiments in miceBone loss

Paper

AntioxidantsOct 27

Sulforaphane as a Therapeutic Target for Sarcopenia in Type 2 Diabetes: Mechanistic Insights and Translational Evidence

Sulforaphane is abundant in cruciferous vegetables.

ReviewSarcopenia

Paper

NutrientsOct 27

Exercise Is Associated with Skeletal Muscle Autophagy-Lysosome-Related Markers and Nrf2/ARF1 Signaling in HFD Mice

Changes in the body weight of each group of mice: (A) the weight changes of the DC and HFD groups before the intervention, * p < 0.05, ** p < 0.01 vs. DC; (B) the changes in body weight of different…

Experiments in 40 miceExercise

Paper

NutrientsOct 27

Dietary Sulfur Amino Acid Sensing and Metabolic Adaptation: From the GCN2-ATF4-FGF21 Axis to Transsulfuration and Redox Homeostasis

Integrated sulfur amino acid sensing and metabolic adaptation through the GCN2–ATF4–FGF21, transsulfuration, and SAMTOR–mTORC1 pathways.

ReviewInterventions

Paper

Monday, October 26

Scientific ReportsOct 26

A regulatory RNA segment eases osteoporosis in mice

In an experiment in mice with their ovaries removed, the RNA segment eased physical features of osteoporosis.In an experiment in mice with their ovaries removed, the RNA segment eased physical features of osteoporosis.

Mouse studyBones and joints

Paper

ESC Congress 2026 AbstractOct 26

Metabolic protein limited blood vessel growth in engineered mice

Deleting the protein’s gene reversed impaired vessel growth in mice engineered to have blood vessel lining cells that had stopped dividing.Deleting the protein’s gene reversed impaired vessel growth in mice engineered to have blood vessel lining cells that had stopped dividing.