Papers on epigenetic clock

1,667 papers43 new in 30 days

Thursday, September 3

Neuroscience and Biobehavioral ReviewsSep 3

Criminal legal system contact and markers of biological aging: A systematic review

Figure from Neuroscience and Biobehavioral Reviews

Systematic review of observational studiesPopulations

Paper

Sichuan Da Xue Xue Bao Yi Xue BanSep 3

Research Advances on Mechanisms and Interventions of DNA Methylation-Regulated Aging-Related Imbalance in Bone Metabolism

Methylation modifications and methylation clock during aging 衰老中的甲基化修饰与甲基化时钟 SAM: s-adenosylmethionine; Me: methylation.

ReviewMethionine and one-carbon metabolism

Paper

GSC Advanced Research and ReviewsSep 3

ACCELERATED BIOLOGICAL AGING: ENVIRONMENTAL, LIFESTYLE, AND SOCIAL DETERMINANTS OF EPIGENETIC AGE ACCELERATION: A SYSTEMATIC REVIEW

Systematic reviewPopulations

Paper

Wednesday, September 2

Frontiers in MedicineSep 2

Spatial niche remodeling of senescent liver-resident immune cells and its role in chronic liver diseases

Hepatic lobular immune zonation and the three dimensions of spatial niche remodeling.

ReviewCellular senescence

Paper

Monday, August 31

Circulation Population Health and OutcomesAug 31

Assessing Differences Between Epigenetic versus Chronologic Age for Cardiovascular Risk Assessments in the United States

Cohort study of 1,516 peopleCardiovascular disease

Paper

Sunday, August 30

Research SquareAug 30

In-depth characterization of the DNA methylation aging landscape links epigenetic noise and genotype-specific epigenetic aging to inflammaging

Preprint: study in peopleDNA methylation

Paper

Nature CommunicationsAug 30

Associations between diet quality, epigenetic aging and epigenome in two population-based cohorts

Correlation across diet-quality scores in the Rhineland Study.

Cohort study in peoplePopulations

Paper

Saturday, August 29

Ageing Research ReviewsAug 29

Living beyond our evolutionary warranty: Why non-communicable diseases may be the inevitable costs of an extended lifespan

ReviewMechanisms

Paper

Frontiers in MedicineAug 29

From skin aging biomarkers to precision esthetic longevity: a translational diagnostic framework

The proposed framework integrates five complementary diagnostic layers: systemic biological context, skin- and tissue-specific molecular biology, functional tissue behavior, imaging-based and…

ReviewBiomarkers

Paper

bioRxivAug 29

MOSurvivor-Guided Joint CpG Selection and XGBoost Hyperparameter Optimization for Compact Epigenetic Age Prediction

Preprint: computational studyBiomarkers

Paper

Friday, August 28

The Journals of Gerontology, Series AAug 28

Biological age associates with longitudinal frailty-related functional decline: the Health and Retirement Study

Cohort study of 4,018 peopleBiomarkers

Paper

Frontiers in MicrobiologyAug 28

High-fructose diet-induced gut dysbiosis as a mechanistic driver of chronic inflammation and accelerated biological aging: a comprehensive review

High-fructose diet–induced perturbation of intestinal microecology and initiation of the gut–liver inflammatory axis.

ReviewMicrobiome composition

Paper

bioRxivAug 28

Epigenetic Clocks Reveal Age Acceleration and Shared Methylation Remodeling Across Cancers

A: Age distribution of all tumor and normal samples, B: Distribution of normal and tumor samples in 8 cohorts

Preprint: computational studyEpigenetic clock

Paper

Thursday, August 27

International Journal of Gynaecology and ObstetricsAug 27

The womb as the cradle of longevity: Perinatal origins of biological aging

ReviewPopulations

Paper

International Journal of Molecular SciencesAug 27

DNA Methylation as a Programmable Information Layer: From Molecular Marks to Disease State Engineering

DNA methylation as a programmable information layer across biological scales.

ReviewDNA methylation

Paper

GenesAug 27

Non-Human Primates as a Comprehensive Model for Studying Epigenetic Markers of Aging

An overview establishing non-human primates as the premier model system for aging research due to their unique relevance to human biology.

ReviewMechanisms

Paper

Nature CommunicationsAug 27

The OmniAge compendium of aging omic biomarkers links mitotic clocks to clonal hematopoiesis and causality

Graphical summary of the OmniAge R/Python package.

Computational studyBlood and immune system

Paper

Wednesday, August 26

MetabolitesAug 26

Visceral Obesity and Its Complications: The Role of Bioelectrical Impedance Analysis in Longevity Medicine

Mechanistic progression from visceral adiposity to age-related disease, highlighting cross-cutting mechanisms discussed critically throughout Section 3 and Section 4.

ReviewVisceral obesity

Paper

Tuesday, August 25

Research SquareAug 25

The reset of aging counters in the germline and early embryo: a systematic review of centriole, telomere, mitochondrial, and epigenetic clocks across seven developmental transitions

Preprint: meta-analysisTelomerase and telomere maintenance

Paper

Saturday, August 22

GeroScienceAug 22

Integrating biological aging into clinical practice: a review and path forward for precision longevity medicine

ReviewBiomarkers

Paper

Nature MedicineAug 22

Responsiveness of epigenetic aging biomarkers to longevity interventions in humans

Current paradigms to study the responsiveness of DNAm biomarkers and their limitations.

Computational studyBiomarkers

Paper

Thursday, August 20

iScienceAug 20

The applicability of DNA methylation-based tools in a low-income, sub-Saharan African population: Malawi longitudinal study of families and health

Cohort study of 49 peopleBiomarkers

Paper

NatureAug 20

Lab-grown human brain models recorded developmental time

Human brain organoids grown for five years showed cell-type-specific changes in gene activity and DNA-based age estimates that tracked time in culture.Human brain organoids grown for five years showed cell-type-specific changes in gene activity and DNA-based age estimates that tracked time in culture.