Computational tests on 4,798 blood samples found that replacing missing readings with zero produced stronger bias that varied with the size of aging-clock estimates.Computational tests on 4,798 blood samples found that replacing missing readings with zero produced stronger bias that varied with the size of aging-clock estimates.

Computational studyBiomarkers

Paper

Epigenetics CommunicationsJul 20

Epigenome-wide association study uncovers aging-related genes and enriched pathways in liver transplant recipients

Cohort study in peopleMechanisms

Paper

Sunday, July 19

Clinical, Cosmetic and Investigational DermatologyJul 19

Genetically Proxied Biological Aging and Risk of Hypertrophic Scar/Keloid-Coded Phenotypes: An Exploratory Two-Sample Mendelian Randomization Study

Mendelian randomization in peopleMechanisms

Paper

Saturday, July 18

Russian Ophthalmological JournalJul 18

Biomarkers of aging. Part 1. General state of the problem and approaches to assessing biological age

ReviewBiomarkers

Paper

Friday, July 17

Cell Stem CellJul 17

Vitamin C attenuates primate bone marrow aging at the molecular and progenitor level

Experiments in non-human primatesVitamin C

Paper

Monday, July 13

PNASJul 13

Age-associated epigenetic drift trajectory and cross-national disparities in accelerated aging in domestic dogs

Experiments in dogsEpigenetic regulation of gene expression

Paper

GeroScienceJul 13

Distinct epigenetic ageing patterns are associated with heterogeneity in kidney function decline in type 2 diabetes

Cohort study of 607 peopleType 2 diabetes

Paper

Sunday, July 12

European Archives of Psychiatry and Clinical NeuroscienceJul 12

Accelerated aging in schizophrenia: integrating epigenetic clocks, telomere dynamics, senescence-associated secretory phenotype, and oxidative stress

ReviewSenescence-associated secretory phenotype

Paper

Friday, July 10

ZenodoJul 10

The Substrate Collapse: Hemispheric Decoherence, Mirror Neuron Atrophy, and the Emerging 40–50 Mortality Horizon

Preprint: meta-analysis of studies in peoplePopulations

Paper

Thursday, July 9

GeroScienceJul 9

Age-associated DNA methylation patterns in mouse blood and tail: feasibility of tissue-specific epigenetic clock development

Experiments in miceEpigenetic clock

Paper

Aging CellJul 9

Standard risk factors outperformed DNA aging clocks

Among 1,108 adults aged 34 to 49, standard risk factors predicted chronic disease over seven to nine years better than DNA-based aging measures.Among 1,108 adults aged 34 to 49, standard risk factors predicted chronic disease over seven to nine years better than DNA-based aging measures.

Cohort · 1,108 peopleBiomarkers

Paper

Wednesday, July 8

Clinical EpigeneticsJul 8

Exploring a targeted epigenetic clock based on mortality-associated CpGs as a potential biomarker for frailty

Cohort study of 446 peopleEpigenetic clock

Paper