6 papers
A cross-sectional analysis of 15,612 adults aged 55–80 screened for Alzheimer’s trials found blood marker differences between racial and ethnic groups.A cross-sectional analysis of 15,612 adults aged 55–80 screened for Alzheimer’s trials found blood marker differences between racial and ethnic groups.
An overall thinking score matched an established measure in classifying progression to mild cognitive impairment, with a performance score of 0.70.An overall thinking score matched an established measure in classifying progression to mild cognitive impairment, with a performance score of 0.70.
Over a median 5.1 years, bleeding-related lesions appeared in 33.7% of participants with severe enlargement versus 13.6% without severe enlargement.Over a median 5.1 years, bleeding-related lesions appeared in 33.7% of participants with severe enlargement versus 13.6% without severe enlargement.
In 602 discovery and 2,313 validation participants, associations between plasma pTau217 and brain pathology were stronger among people with lower periventricular…In 602 discovery and 2,313 validation participants, associations between plasma pTau217 and brain pathology were stronger among people with lower periventricular diffusivity.
In a longitudinal cohort, lifetime alcohol use disorder was associated with steeper cognitive decline, equivalent to 7.1 additional years of cognitive aging at age 60.In a longitudinal cohort, lifetime alcohol use disorder was associated with steeper cognitive decline, equivalent to 7.1 additional years of cognitive aging at age 60.
In a study of 2,249 adults, a remote test discriminated cognitive impairment with an AUC of 0.89, rising to 0.95 when confirmed by amyloid biomarkers.In a study of 2,249 adults, a remote test discriminated cognitive impairment with an AUC of 0.89, rising to 0.95 when confirmed by amyloid biomarkers.