Aβ42/Aβ40 ratio

Biomarker5 papers2 findings

Human trial1
Humans4

Upstream

1

MMP9

mediatesin humans1

1 study

MMP9 mediates Aβ42/Aβ40 ratio in humans.
Humansamong APOE4+ carriers only, mediating effect of CX3CL1 on Aβ42/Aβ40
Matrix metalloproteinase-9 is associated with CX3CL1 on tau and amyloid biomarker pathways in APOE4 carriers · Neurobiology of disease · 13 Sep 2026

Associations

1

APOE

downin humans1

1 study

APOE is associated with Aβ42/Aβ40 ratio in humans.
HumansAPOE4+ carriers vs non-carrierscerebrospinal fluid
Matrix metalloproteinase-9 is associated with CX3CL1 on tau and amyloid biomarker pathways in APOE4 carriers · Neurobiology of disease · 13 Sep 2026

Latest

7

Frontiers in NeurologyReviewYesterday

Associations between obstructive sleep apnea and Alzheimer's disease-related biomarkers (amyloid-β and tau) in blood and cerebrospinal fluid: a systematic review and meta-analysis

Obstructive sleep apnea

Experimental NeurologyAnimals2 Oct

Fluid amyloid-β (Aβ) biomarkers reflect early β-sheet-rich Aβ deposition during the preclinical stage in Alzheimer's disease model 5XFAD mice

medRxivHumansPreprint24 Sep

Association of plasma biomarkers with longitudinal change in age- and Alzheimer's disease-related brain atrophy patterns

Alzheimer's disease

npj AgingHumans17 Sep

Associations of physical fitness with brain structure, pathology and cognition in cognitively normal older adults

Neurobiology of DiseaseHumans13 Sep

Matrix metalloproteinase-9 is associated with CX3CL1 on tau and amyloid biomarker pathways in APOE4 carriers

Research SquareHumansPreprint9 Sep

Plasma Fibrinogen Correlates with Aβ Clearance of monocytes and AD Biomarkers in Cognitively Normal Individuals

Alzheimer's & DementiaHuman trial9 Sep

More efficient screening for preclinical Alzheimer's clinical trials using mixture of experts

Alzheimer's disease