Chinese Journal of Geriatrics·Oct 22Expression characteristics and clinical significance of peripheral blood T cells CD28 and PD-1 in elderly patients with pulmonary tuberculosisCohort study of 248 peopleCD28Paper
HIV Medicine·Sep 11The effect of a tailored dietary intervention on serum biomarkers and faecal microbiome composition in people with HIV at risk of cardiovascular diseaseNon-randomized trial in 10 peopleDietary interventionPaper
Nature Aging·Aug 27Cytotoxic CD4⁺ T cells induce age-associated myelopoiesis through CCL5-CCR5 signalingExperiments in miceBlood and immune systemPaper
Journal of the American Heart Association·Mar 10Specific Deficiency of Naïve CD4+ T Lymphocytes Characterizes Heart Failure and Heightens Mortality Risk in the HRSCohort study of 38,565 peopleHeart failurePaper
Aging Cell·Mar 7Physical Fitness Dynamics Shape Immune Remodeling in Healthy Aging: A 3-Year Longitudinal StudyCohort study of 49 peopleBlood and immune systemPaper
BMC Cardiovascular Disorders·Oct 14Immunological biomarkers and molecular signatures in healthy aging: early dynamics of subclinical atherosclerosis in a homogeneous elderly cohortCross-sectional study of 79 peopleAtherosclerosisPaper
Frontiers in Immunology·Sep 11The endoplasmic reticulum stress status of CD4+ T lymphocytes and its association with mTOR-mediated autophagic-lysosomal disorder in elderly sepsis patientsCohort study of 62 peopleER unfolded protein responsePaper
medRxiv·Jun 6Loss of Y chromosome in Alzheimer disease patients co-occurs with clonal hematopoiesis defined by post-zygotic point mutations outside canonical CHIP driver genesPreprint: case-control study in peopleBlood and immune systemPaper
Biochimie·Apr 11Phenotypic changes associated with continuous long term in vitro expansion of bone marrow-derived mesenchymal stem cellsExperiments in human cellsSenescence-associated secretory phenotype (SASP)Paper
European Geriatric Medicine·Oct 30Association between a lower T-CD4+ /CD8+ lymphocyte ratio and cognitive impairment in older persons with HIVCross-sectional study of 207 peopleCognitive impairmentPaper
Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine]·Feb 23Association between CD4⁺T lymphocyte and body composition with physical frailty among elderly HIV-infected patients in Chongqing CityCross-sectional study of 485 peoplePopulationsPaper
Experimental Gerontology·Feb 13Does excess body weight accelerate immune aging?Cross-sectional study of 103 peopleBiomarkersPaper
Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii·Dec 29THE INFLUENCE OF THE WAR FACTOR ON AGE CHANGES IN THE SUBPOPULATION STRUCTURE OF LEUCOCYTES AS A COMPONENT OF INFLAMMAGING IN THE GROUPS OF MILITARY PERSONNEL AND CLEAN-UP WORKERS OF THE CHORNOBYL ACCIDENTCross-sectional study of 397 peopleInflammationPaper
Advanced Science·Nov 22Extracellular Delivery of Functional Mitochondria Rescues the Dysfunction of CD4⁺ T Cells in AgingExperiments in miceBlood and immune systemPaper
Immunity & Ageing·Aug 13Systemic immune response in young and elderly patients after traumatic brain injuryCase-control study in peopleImmune responsePaper
Frontiers in Immunology·Jan 18Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammationExperiments in miceFisetinPaper
Zhonghua Liu Xing Bing Xue Za Zhi·Dec 2Neurocognitive impairment and characteristics of neurocognitive performance among people with HIV on antiretroviral treatmentStudy in peoplePopulationsPaper
Genes & Development·May 27Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillanceExperiments in miceSenescence-associated secretory phenotype (SASP)Paper
International Journal of Molecular Sciences·Mar 11Senescent CD4⁺CD28⁻ T Lymphocytes as a Potential Driver of Th17/Treg Imbalance and Alveolar Bone Resorption during PeriodontitisReviewCellular senescencePaper
Oxidative Medicine and Cellular Longevity·Jan 1Immunophenotypic Analysis of T Lymphocytes and Cytokine Production in Elderly Practicing Physical Activities and Its Relationship with Quality of Life and DepressionCross-sectional study of 48 peoplePhysical activityPaper
Pharmaceutics·Sep 10The Protective Effect of Topical Spermidine on Dry Eye Disease with Retinal Damage Induced by Diesel Particulate Matter2.5Experiments in ratsSpermidinePaper
Immunologic Research·Aug 21Analysis of the dynamic changes in the proportion of immune cells and the proportion of cells with stem cell characteristics in the corresponding immune cell population of C57 mice during the natural aging processExperiments in miceImmune responsePaper
Frontiers in Immunology·Jul 30Identification of the Immunological Changes Appearing in the CSF During the Early Immunosenescence Process Occurring in Multiple SclerosisCross-sectional study of 263 peopleMechanismsPaper
Aging·Mar 30Chronic treatment with acetaminophen protects against liver aging by targeting inflammation and oxidative stressExperiments in miceInterventionsPaper
Aging and Disease·Dec 4Premature CD4⁺ T Cells Senescence Induced by Chronic Infection in Patients with Acute Coronary SyndromeCross-sectional study of 25 peopleCellular senescencePaper
Ageing Research Reviews·Nov 29Thymus involution sets the clock of the aging T-cell landscape: Implications for declined immunity and tissue repairReviewBlood and immune systemPaper
BMC Cancer·Sep 16Immunosenescence profile and expression of the aging biomarker (p16INK4a) in testicular cancer survivors treated with chemotherapyCase-control study of 16 peopleBiomarkersPaper
Cell Metabolism·May 14CD4⁺ T Cells at the Center of InflammagingCommentaryBlood and immune systemPaper
Scientific Reports·Apr 16Cigarette smoking induces human CCR6⁺Th17 lymphocytes senescence and VEGF-A secretionExperiments in human cellsCellular senescencePaper
Aging·Nov 11Age-associated changes in human CD4⁺ T cells point to mitochondrial dysfunction consequent to impaired autophagyCross-sectional study in peopleOxidative phosphorylationPaper