AIM2
GeneHomo sapiens2 papers1 findingHGNC 357NCBI Gene 9447Taxon 9606
- Humans1
Upstream
1ASXL1
upin human cells1
1 study
ASXL1
upin human cells1
ASXL1 activates AIM2 in human cells.
CellsASXL1-mutant human THP-1-derived macrophage-like cellsmacrophage
ASXL1 mutations in clonal hematopoiesis accelerate aortic valve calcification · medRxiv · 29 Sep 2026 · Preprint
Latest
2ASXL1 mutations in clonal hematopoiesis accelerate aortic valve calcification
Large human cohort data and cell experiments show that ASXL1-driven clonal hematopoiesis worsens aortic valve hemodynamics and promotes calcification through inflammatory signaling.
medRxiv · Small A et al.
Mitochondrial Quality Control Links Exercise to Sterile Inflammation in the Cardiovascular System: A Narrative Review
ReviewAntioxidants (Basel, Switzerland)