TG2 inhibition

1 paper2 findings

Outcomes

2

Autophagy

upin reviews1

1 study

TG2 inhibition increases autophagy.
“selective TG2 inhibition restores autophagic flux, mitigates mitochondrial damage, and reduces aggregate burden in preclinical models.”
Reviewin preclinical models of Alzheimer's disease
Transglutaminase and its role in Alzheimer's disease: focus on mitochondria, aging, defective mitophagy, synaptic degeneration, and metabolomics
GeroScience25 May 2026

More on Autophagy

Mitochondrial damage

downin reviews1

1 study

TG2 inhibition decreases mitochondrial damage.
“Therapeutically, selective TG2 inhibition restores autophagic flux, mitigates mitochondrial damage, and reduces aggregate burden in preclinical models.”
Reviewin preclinical models of Alzheimer's disease
Transglutaminase and its role in Alzheimer's disease: focus on mitochondria, aging, defective mitophagy, synaptic degeneration, and metabolomics
GeroScience25 May 2026

Latest

1 in 12 months

GeroScience26 May

Transglutaminase and its role in Alzheimer's disease: focus on mitochondria, aging, defective mitophagy, synaptic degeneration, and metabolomics

ReviewMitophagy