Sterol

Intervention

2 papers study it140 more mention it1 finding

PubChem

Funders: National Institute of General Medical Sciences and 1 more

Associations

Lifespan

mixedin flies1

1 study

Sterol is associated with lifespan in flies.
“which involves a trade-off between lifespan and reproduction, but in a manner that is conditional on the dietary supply of an essential micronutrient - a sterol.”
Reviewfemales
Dietary restriction and lifespan: adaptive reallocation or somatic sacrifice?
The FEBS journalApr 26, 2022

Funding

2 grants since 2017

National Institute of General Medical SciencesUS$881.1kNational Heart, Lung, and Blood InstituteUS$712.7k

Control Sterol and Lipoprotein Homeostasis by miRNA
National Heart, Lung, and Blood InstituteSaint Louis UniversityUS$351.9k2011–2021
Structural Requirements for Sterol 14alpha-Demethylases
National Institute of General Medical SciencesVanderbilt UniversityUS$409.1k2004–2019

Latest

26 papers in 12 months

Analytica Chimica ActaOct 17

RP-UHPLC/MS/MS reveals statin-induced alterations in profiles of free monohydroxy sterols and tocopherols in human plasma

Cross-sectional study of 41 peopleStatins

Paper

The American Journal of Clinical NutritionOct 17

Dietary supplementation with plant sterols for obesity management and related metabolic disorders: A randomized, double-blind, placebo-controlled crossover clinical trial

Randomized trial in 23 peopleMetabolic disorders

Paper

Journal of the American Heart AssociationOct 16

Genetic analysis links shared DNA signals to artery disease

An observational analysis of human genetic study results identified 289 lead DNA variants across 177 risk regions and prioritized candidate protein targets.An observational analysis of human genetic study results identified 289 lead DNA variants across 177 risk regions and prioritized candidate protein targets.

Genetic association studyMechanisms

Paper

Frontiers in PhysiologyOct 15

Beyond traditional coconut oil: metabolic effects of medium-chain triglyceride oil-mechanistic insights, lipid remodeling, and clinical implications in cardiometabolic health

ReviewLipid and ceramide metabolism

Paper

GeneticsSep 29

KLF-1 regulates SKN-1 activity and longevity in worms

In germline-deficient animals, KLF-1 was required for SKN-1 activation, oxidative stress resistance, and longevity without altering skn-1 transcript abundance.In germline-deficient animals, KLF-1 was required for SKN-1 activation, oxidative stress resistance, and longevity without altering skn-1 transcript abundance.

Experiments in wormsMechanisms

Paper

GeroScienceSep 23