Natural products

1. Natural products inhibit apoptosis.

   Reviewvia Bcl-2/Bax/caspase signalingkidney

   The Role of Natural Products in Ameliorating Mitochondrial Dysfunction in Diabetic Kidney Disease and the Underlying Mechanisms · Mini reviews in medicinal chemistry · 30 Sep 2026

Apoptosis →

1. Natural products induce mitophagy.

   ReviewPINK1/Parkin- or BNIP3-mediatedkidney

   The Role of Natural Products in Ameliorating Mitochondrial Dysfunction in Diabetic Kidney Disease and the Underlying Mechanisms · Mini reviews in medicinal chemistry · 30 Sep 2026

Mitophagy →

1. Natural products activate mitochondrial biogenesis (PGC-1α).

   Reviewvia AMPK/SIRT1/PGC-1alpha pathwaykidney

   The Role of Natural Products in Ameliorating Mitochondrial Dysfunction in Diabetic Kidney Disease and the Underlying Mechanisms · Mini reviews in medicinal chemistry · 30 Sep 2026

Mitochondrial biogenesis (PGC-1α) →

1. Natural products decrease mitochondrial dysfunction.

   Reviewin diabetic kidney diseasekidney

   The Role of Natural Products in Ameliorating Mitochondrial Dysfunction in Diabetic Kidney Disease and the Underlying Mechanisms · Mini reviews in medicinal chemistry · 30 Sep 2026

Mitochondrial dysfunction →